1. Indications/Uses
- Evaluate tracheal and lower airway diseases
- Obtain samples (bronchoalveolar lavage)
- Remove foreign bodies
2. Contraindications
- Unstable patient condition unable to tolerate anesthesia
- Significant coagulation disorders
- Partial tracheal obstruction
- Unstable asthma
- Pulmonary hypertension
3. Equipment
- Flexible endoscope: 2.5–6 mm in diameter, 50–80 cm in length
- Endoscopic viewing equipment
- Topical anesthetic spray
- Mouth gag
- Elbow connector (Figure B.41): Used to connect the endotracheal tube (ET tube) to the breathing circuit, allowing endoscope insertion while delivering oxygen and volatile anesthetics
- Pulse oximeter
- Foreign body retrieval instruments: Forceps (including basket, rat-tooth, alligator, net, and polyp snare types)
3.1 Bronchoscope
The preferred
bronchoscope is a fiberoptic endoscope with a diameter of 3.5–6.0 mm and a working length of at least 55 cm. This is a typical size for human bronchoscopes, and a 5 mm diameter endoscope is suitable for most dog sizes.
Cats require narrower bronchoscopes for endoscopy. A 55 cm working length endoscope may be too short to fully examine the lobar bronchi of large dogs.
Longer veterinary endoscopes are available to address this issue, but gastroscopes/duodenoscopes can also be used. Although such endoscopes can be up to 8 mm in diameter, airway obstruction is relative due to the larger size of dogs.
A limitation of using endoscopes longer than 55 cm with a diameter <6 mm or narrower sizes is that images are often less clear due to fewer light-transmitting optical fibers. A recent advancement addressing this is the development of video bronchoscopes.
Figure 1: Connecting the endotracheal tube to the breathing circuit using an elbow port.
4. Animal Preparation and Positioning
Inhalational anesthesia is recommended; however, intubation should only be performed if the endoscope can easily pass through the endotracheal tube, allowing simultaneous movement of air and the endoscope. An elbow port connector can be used to provide continuous gas anesthesia while the endoscope passes through the endotracheal tube.
If the endoscope cannot pass through the endotracheal tube, intravenous anesthesia must be used. To reduce the risk of hypoxemia, additional oxygen can be delivered alongside the bronchoscope via a urinary catheter or other type of flexible thin catheter. A flow rate of 1–3 liters per minute can be safely used.
Pre-oxygenation is highly beneficial, especially if oxygenation is impaired. This can be provided via nasal oxygen catheter or face mask.
The patient should be placed in a prone position with the head elevated and neck extended (Figure B.42). However, some clinicians prefer lateral recumbency as it facilitates easier manipulation, insertion, and maneuvering of the endoscope.
A mouth gag is essential to keep the mouth open and prevent the endoscope from being bitten due to the gag reflex triggered by endoscope contact with the pharynx.
Figure 2: Prone position of the animal for bronchoscopy. Intubation must be removed, and the endoscope inserted directly into the trachea unless using a very narrow-diameter endoscope.
4.1 Warning
Extra caution is required when the endoscope is placed in the airway without oxygen delivery, as severe hypoxemia may occur. Therefore, pulse oximetry must be closely monitored. Additionally, the endoscope may interfere with ventilation, leading to hypercapnia, pulmonary hyperventilation, trauma, and bronchospasm.
5. Special Considerations for Cats
Cats require extra care during bronchoscopy as their airways are particularly prone to bronchospasm.
The procedure should be completed as quickly as possible to minimize trauma.
Due to cats' susceptibility to laryngospasm, lidocaine should be sprayed on the larynx before intubation. Clinicians should wait 30–60 seconds for the lidocaine to anesthetize the larynx, then insert the tube gently; intubation should only be performed when the larynx is open, using a twisting motion.
If using a commercial topical lidocaine spray, clinicians should be aware of the dose delivered per pump, as repeated use may cause toxicity. A dose of 1 mg/kg of 2% lidocaine is appropriate for cats (i.e., approximately 0.2 ml for a 4 kg cat).
To reduce the risk of bronchospasm, terbutaline (0.015 mg/kg subcutaneously or intramuscularly) can be administered approximately 30 minutes before bronchoscopy. Onset of action is 15–30 minutes, which can usually be observed by an increase in heart rate.
Terbutaline should also be available for administration if bronchospasm occurs during the procedure. If this fails to stabilize the animal, short-acting corticosteroids (e.g., dexamethasone sodium phosphate 0.1 mg/kg intravenously once) should be considered.
Suction equipment (or a 10–20 ml syringe connected to a sterile urinary catheter) should be available to clear any secretions from the oropharynx. If possible, cats should remain prone during the procedure. If a cat resists oropharyngeal suctioning, re-induction of anesthesia may be necessary to effectively clear the upper airway.
6. Operational Technique
- For cats, spray topical anesthetic on the larynx and wait 30–60 seconds.
- Advance the endoscope to the larynx and examine the area (Figure 3).
- If intubating, assess the proximal trachea before intubation. Intubation can be performed after estimating the length of the trachea that will be covered by the endotracheal tube.
- Center the endoscope while advancing it; take care not to irritate the tracheal surface with the endoscope.
- As the endoscope advances, the carina or bifurcation will come into view. The animal's right side is on the operator's left; therefore, the right main bronchus will be seen on the left side of the image. The left and right main bronchi branch clearly with sharp edges (Figure 4).
- The right main bronchus is in a straight line with the trachea and should be examined first.
- Then advance the endoscope into the left main bronchus.
- Evaluate the segmental and subsegmental airways on both the left and right sides as thoroughly and systematically as possible.
- Collect samples (bronchoalveolar lavage) as needed.
- After bronchoscopy, continue administering 100% oxygen and volatile anesthetics for 5 minutes to allow time to detect any immediate complications (e.g., bronchospasm). During the procedure and recovery period, the animal's respiratory rate and pattern should be continuously monitored, preferably with pulse oximetry, to observe for complications such as dyspnea and hypoxemia.
- Supplemental oxygen may be required after extubation until the animal can maintain a prone position and pulse oximetry shows adequate oxygen saturation (SpO2 > 95%). Respiratory pattern and rate should be monitored in the hospital for the next 12 hours.
- If complications occur during recovery and hypoxemia and dyspnea cannot be rapidly reversed with medication, re-induction of anesthesia for intubation and ventilation may be necessary to increase oxygenation and allow investigation to determine the cause of dyspnea.
7. Foreign Body Retrieval
- Position the endoscope a few centimeters proximal to the foreign body.
- Insert the retrieval forceps in a closed position through the biopsy channel (if space permits) or alongside the endoscope.
- Open the forceps, grasp the foreign body, and close the forceps.
- Remove the endoscope and forceps simultaneously.
Figure 3: Prone position of the animal for bronchoscopy. Intubation must be removed, and the endoscope inserted directly into the trachea unless using a very narrow-diameter endoscope.
Figure 4: Lung Anatomy
- Right lung: Cranial lobe, Middle lobe, Caudal lobe, Accessory lobe
- Left lung: Cranial lobe, Caudal lobe
7.1 Warning
Adequate ventilation must be ensured during foreign body retrieval.Foreign body retrieval can be very challenging. Surgeons should be prepared to stop the procedure and plan for surgery if the operation takes too long.There is a risk of airway injury or rupture and pneumothorax. Therefore, thoracentesis or thoracostomy tube placement equipment should be available.
8. Potential Complications
- Hypoxemia
- Bronchospasm
- Laryngospasm and coughing
- Hemorrhage
- Pneumothorax
Nick Bexfield
BVetMed PhD DSAM DipECVIM-CA PGDipMEdSci PGCHE FHEA MRCVS
Julia Riggs
MA VetMB AFHEA DipECVS MRCVS